One week shy of the 50th anniversary of the first human spaceflight, NASA astronaut Ron Garan and Russian cosmonauts Andrey Borisenko and Alexander Samokutyaev launched to the International Space Station at 6:18 p.m. EDT Monday (4:18 a.m. local time, April 5) from the Baikonur Cosmodrome in Kazakhstan. The Soyuz rocket that lifted Garan, Borisenko and Samokutyaev into orbit was decorated with Yuri Gagarin’s name. The mission lifted off from the same launch pad used April 12, 1961, when Gagarin became the first human to journey into space.

The crew is scheduled to dock its Soyuz TMA-21 spacecraft to the station’s Poisk port at 7:18 p.m. on Wednesday, April 6. The crew members will join Expedition 27 Commander Dmitry Kondratyev and Flight Engineers Cady Coleman of NASA and Paolo Nespoli of the European Space Agency, who have been aboard the orbiting laboratory since December 2010. On Wednesday, NASA Television will broadcast live coverage of the docking beginning at 6:45 p.m.